Practical teaching in Economics and Management major is the key to improve students' professional practice ability, so it is necessary to examine the influencing factors of practical teaching effect. In this paper, the path analysis method is used to investigate the direct and indirect effects of four variables, namely, the level of teachers' organization and management, the level of students' input, the level of cooperation between teachers and students, and the level of environmental protection, on the effectiveness of training. The results show that the effective organization and management of instructors play a major role in the level of students' involvement; the level of students' involvement and the level of cooperation between teachers and students have a greater impact on the effectiveness of training, and the effective coordination of a variety of influencing factors can help improve the effectiveness of training.