The education informatization has developed rapidly, and the construction and promotion of MOOC has made it a reality to share high-quality education resources. The proportion and advantages of online teaching are particularly prominent, but some problems have also been exposed in its implementation. In view of the problems existing in the teaching of programming courses, the blended teaching for this kind of courses is explored based on the OBE concept. A new blended teaching model based on the principle of reverse design is proposed, which is "Defining learning output—Realizing learning output—Assessing learning output—Using learning output". The main steps of course construction and teaching implementation includes: determining course objectives, determining teaching content, dividing knowledge modules, constructing course resources, designing teaching strategies, implementing blended teaching, and assessment feedback. Practice has proved that the new model based on reverse design can effectively improve the course teaching quality.