The version origin and compilation process of Annotations to the Plants and Animals in Mao Poetry written by Jiao Xun can be clarified by comparing the 20-volume manuscript collected in Fu Si-nian Library of Taipei Academia Sinica, the one volume manuscript, the 30-volume manuscript and the 11-volume manuscript kept in Shanghai Library. The 11-volume manuscript was revised mainly based on the 30-volume manuscript, referring to the 20-volume and the one volume and other early manuscripts at the same time. The 30-volume manuscript laid the foundation for the compilation of the 11-volume manuscript in terms of content and style. After that, Jiao Xun took the 30-volume manuscript as the base and made a series of adjustments, including adjusting the compilation style, correcting errors, changing the arguments and so on. He finished the definitive edition in 1799. Investigating the compilation process and edition source of this book is conducive to the study of Jiao Xun's academic achievements.