From the perspective of "supply side structural reform" and the internal relevance of ideological education guidance of university students, the study is based on the difficulties faced by ideological education guidance of university students in the new era. Focusing on the fundamental task of "building morality and cultivating people", with the purpose of "integrating resources, invigorating the stock, making sufficient increment and stimulating energy", from the four aspects of supply efficiency, supply mechanism, supply platform and supply benchmark, the study explores and optimizes the new mode, new method and new path of ideological education guidance of university students, so as to accurately serve the growth and development of students.