基于区域竞争力理论，从“软实力”和“硬实力”两大维度构建了区域综合竞争力定量测度评价指标体系，采用因子分析提取了经济综合因子、教育科技因子和居民生活水平因子，运用熵值法赋权，对安徽省16个地级市区域综合竞争力进行实证评价分析。研究发现：安徽省各区域综合竞争力差距悬殊，两极分化严重；排名靠前的城市大多数距省会城市相对较近，总体排名稳定。排名靠前的城市在“硬实力”上的表现优于“软实力”，而排名靠后的城市表现相反。同时，找出制约各区域发展主要因素，提出相应建议措施，以缩小各区域发展差异，提升综合竞争力，加快区域协调一体化、高质量发展。

Based on the theory of regional competitiveness, this paper constructs a quantitative evaluation index system of regional comprehensive competitiveness from two dimensions of "soft power" and "hard power", extracts economic comprehensive factors, education, science and technology factors and residents忆 living standard factors by factor analysis, and makes an empirical evaluation and analysis of regional comprehensive competitiveness of 16 prefecture-level cities in Anhui Province by entropy method. It is found that there is a wide gap in the comprehensive competitiveness of different regions in Anhui Province, and the polarization is obvious; The top-ranking cities are near the provincial capital, and the overall ranking is stable. The top-ranking cities perform better on "hard power" than on "soft power", while those at the bottom are the opposite. At the same time, the study finds out the main factors that restrict regional development, and puts forward suggestions, to narrow regional development differences, enhance comprehensive competitiveness, and accelerate regional coordination, integration, and high-quality development.