豫鄂皖边区是抗战时期国民党在第五战区建立的一个敌后游击区。为巩固敌后，支持长期抗战，新桂系对游击区展开建设，使其成为敌后抗战的坚实堡垒。国民党对游击队编制和训练使其更加正规化，同时成立了经济游击队。抗战过程中，游击队积极配合正面战场，对敌伪实施破坏、袭击等，为抗战胜利作出一定的贡献。与同时期共产党组织的游击战比较，国民党的游击战存在很多局限，因而削弱了豫鄂皖游击区在华中地区的抗战力量。

The Henan, Hubei and Anhui border area was one of guerrilla areas established by Kuomintang behind the enemy during the Anti-Japanese War. To consolidate the base areas behind the enemy lines, support the long war of resistance, the New Guangxi clique carried out construction of the guerrilla areas and made it a solid fortress behind the enemy. The Kuomintang formalized the guerrilla army by organizing and training it, and at the same time established the economic guerrilla army. In the course of the Anti-Japanese War, the guerrillas actively cooperated with the front battlefield and carried out sabotage and attacks against the enemy and puppet forces, making contributions to the victory of the war. Compared with guerrilla warfare organized by the Chinese Communist Party, the Kuomintang guerrilla warfare has limitations, which weakened the resistance of the guerrilla areas in central China.